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(credit: CBS) The police training simluator she brought to the capitol on Thursday featured a series of videos shown on a big screen. The lawmakers were given a fake gun and presented with visual mock situations including an active shooter at a school and an armed robbery at a warehouse. The simulations were intended to help the lawmakers understand how the laws they pass impact the men and women who put their lives on the line every day to protect everyone. It gives us firsthand knowledge of just a fraction of what they go through on a daily basis, said Rep. Don Coram. Coram and Sen. Kent Lambert both took part in the training and said its not only important when considering police reform, but also when setting public safety priorities. Were going a lot more towards funding of body cameras, which also protects our officers and citizens, Lambert said. Attorney General Cynthia Coffman takes part in the training. (credit: CBS) Attorney General Cynthia Coffman, whose office oversees the Colorado Peace Officer Standards and Training Board, brought the simulator to the state capitol. I thought it would be a great opportunity for our legislators who are making policy about training and law enforcement to actually have an opportunity to experience what it is like to make these judgement calls, Coffman said.
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The Phase 2 proof of concept trial called CoDIFy showed ridinilazole outperformed the antibiotic vancomycin, which is the current standard of care. Ridinilazole demonstrated a large numerical reduction in rates of recurrent disease compared to vancomycin with this difference driven by ridinilazole outperforming vancomycin in the preservation of the gut microbiome. Recurrence of CDI, and the failure to subsequently achieve a sustained clinical response after treatment, is a major issue in the management of the disease, as collateral damage to the gut microbiome by antibiotics such as vancomycin leaves patients vulnerable to disease recurrence. Phase 3 preparations are ongoing as the Company continues to explore options to support the future development of ridinilazole with a interview skills for high school students view to maximising the potential commercial value of this antibiotic. Summit`s preference remains finding a third party collaborator although the Company continues to actively explore other potential options, including funding from government and non-profit organisations. In parallel, Summit is undertaking an exploratory Phase 2 trial called CoDIFy 2 to evaluate ridinilazole against the antibiotic fidaxomicin. This trial is intended to further understand the impact of ridinilazole on a number of disease parameters, including its impact on patients` gut microbiomes to help inform the design of the Phase 3 clinical programme for ridinilazole. Dosing of patients in this trial has now completed, and Summit expects to report top-line data, including analysis of the microbiome, during Q2 2017. The development of ridinilazole has been financially supported by Seeding Drug Discovery and a fantastic read Translational Awards both from the Wellcome Trust. FINANCIAL REVIEW Revenue As part of the exclusive collaboration and license agreement entered into with Sarepta, the Company received an upfront payment of 32.9 million. Of this amount, 0.6 million was recognised during the three months ended 31 October 2016. The remaining 32.3 million of the upfront payment is classified as deferred income and will be recognised as revenue over the development period.
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